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2-Dg for Covid - What Is It and How Does It Work?

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  The DCGI (Drugs Controller General of India) has recently given approval to a drug 2-DG ( 2–deoxy—D—glucose)  for emergency use as an adjunct therapy in moderate to severe Covid-19 patients. Work on this drug was conducted by INMAS (Institute of Nuclear Medicine and Allied Sciences) and the pharma company Dr Reddy's Labs. What is 2-dg? 2-Deoxy-D- Glucose is a modified glucose molecule, modified in a manner that it cannot undergo Glycolysis (breakdown of glucose molecule to release energy and pyruvate).  It has been in existence since a long time, and initial research on this molecule was conducted as long as sixty years ago. How does it Work? The drug works by concentrating in virus-infected cells.   It is supposed to prevent the multiplication of the virus by stopping the growth of the virus.  It selectively reaches viral affected cells. It reduces the body's need for supplemental oxygen and patients can be weaned off earlier from external oxygen support. The...

Home Care for the Covid-19 Patient

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    A large majority of patients who are infected by the Coronavirus are either asymptomatic or mildly symptomatic. Most of them are managed at home. This has multiple benefits- you prevent passing on the infection to multiple other persons, you are in the comfort of your house and can enjoy home food, and most important you do not overwhelm hospitals that need beds to treat seriously ill patients. Credible and respected organizations like WHO, CDC, AIIMS have set up and continue to update protocols for home care of a patient diagnosed with Covid-19. Medication                 1. Tab Paracetamol SOS for fever or body ache                 2. Simple over-the-counter antacid, empty stomach - for acidity                 3.  Simple antitussive cough syrup/cough suppressant for a simple cough Steam inhalation at night - for productive cough Points to Note...

Covid Positive Patient in Apartment Blocks- What to Do?

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Many of us live in Apartment Blocks and as the Corona virus continues to ravage our country we are rightfully concerned about the spread in our homes, specially if someone in the vicinity is diagnosed as positive. There are some facts to consider and some steps to take. For Management Be careful, not paranoid. Avoid instilling unnecessary fear among residents. Take precautions -  STAFF All guards and staff to wear  Masks  at all times - discard masks after duty if 3-ply, wash with warm water and dry in the sun if double/ triple layered cloth mask Guards to wear  Face shields  specially when interacting with outsiders, vendors etc - these can be disinfected at end of day and reused the next day Guards to wear  Gloves  which are disposed off once shift is over FACILITY Keep  hand sanitizers  at all convenient locations including Lifts, Block entrances, Floor entrances Encourage hand washing - dedicated wash basins with Soap...

Testing- What Are the Tests for Coronavirus?

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Testing- What Are the Tests for Coronavirus? "Test, Test, Test," said the DG of WHO at the beginning of the Pandemic outbreak. There was and continues to be a very important reason for that -  The virus is highly contagious so one person can infect many others Many patients are asymptomatic or mildly symptomatic In this situation, the only way to contain the spread of the disease is to diagnose patients early - before they infect others. The only way to do that is by aggressive testing, diagnosing, contact tracing and then isolating the contacts.  So what are the Tests available for diagnosis? These are of two types Checking for Antigen - for the presence of the virus - indicative of fresh infection. Checking for Antibody- for human response to the infection- indicates recent infection. 1. Testing for Antigen RT PCR - the gold standard for testing for the virus. This test is done not by taking blood but by swabs that are inserted into your nose (dee...