Treatment for a Patient of Covid-19 - #Corona Virus


The Corona Virus - SARS CoV-2 causes the disease Covid-19. This is similar to a virus named HIV causing the disease AIDS.
Currently, there is no known treatment for Covid - 19.
There is an intense amount of research but there is no definite breakthrough. 
Molecules to treat diseases take years of testing - Lab, Animal studies, Human trials before they are declared to be fit for human use. The suddenness and the severity of the Coronavirus has given us very little time to develop a new molecule. In this situation various treatments which were successful against Viruses of a similar nature in the past are being tried out - a process called "Repurposing" - a strategy for off label use of known drugs.
To understand treatment strategies for Covid-19 we must break the disease into its stages - because treatment is different at each stage.

Asymptomatic and Pre Symptomatic patients

The good news is that in a large majority of patients there are no symptoms. Apart from home quarantine, adequate rest and nutrition these patients obviously require no treatment. They need to be under observation.

Mild

These patients have a fever with mild Flu-like symptoms- cold, body ache, loss of sense of smell or taste, mild cough.

Moderate

These are patients with Pneumonia without any signs of severe disease. Respiratory rate is below 30 per minute and oxygen saturation (SPO2) is above 90 %.
These patients will need close monitoring under medical supervision - especially of the blood Oxygen levels. Apart from supportive and symptomatic management they may need Oxygen.

Severe

A very small minority of patients will become seriously ill- these are usually elderly, Immune compromised, those with pre-existing illnesses like Diabetes, Hypertension, Heart disease, Kidney ailments. 
They develop Acute Respiratory Distress Syndrome (ARDS), Heart complications, Kidney disease, Clotting disorders etc. These patients will require therapy of some kind, they may also need to be placed on ventilators in case they cannot breathe for themselves.
The various treatment options that are available are
- Anti Viral drugs like Remdesivir and others
- Immune modulators like Hydroxychloroquine - not enough evidence to support its use.
- Convalescent Plasma therapy - using plasma of a plasma who has recovered from Covid-19 and has Antibodies in his blood.
- Anticoagulants and other therapies including kidney dialysis depending upon their requirement.
As we can see - on account of lack of any acceptable treatment protocols it is recommended that Prevention is the best strategy - Physical distance of 2 metres from other humans and frequent handwashing with soap and water.
Stay Safe.

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Lock Down 4 Information By Dr Rajesh Bhardwaj


Location: New Delhi, Delhi, India

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